International Journal of
Advances in Interdisciplinary Research
Journal Metrices
eISSN 2348-0696
SJIF : 6.07 (2022)
Open Access
Bi-Monthly
Peer-Reviewed
Indexed
First decision : 10 days
Acceptance to publications : 3 days
Editor-in-Chief
Dr. S.V. Rajesh Vivekanandha Ramakrishna Mission College , Chennai, India.
Associate Editor(s)
Dr. J. Pradeep Babu
University of Tennessee, Knoxville, USA.
Dr. Seralathan Kamala Kannan
Chonbuk National University, South Korea.
Dr. Nazish Roy
Dong A University, South Korea.
Dr. S. Karunakaran
Department of Chemical Engineering, KPR Institute of Engineering and Technology, Arasur,
Coimbatore-641 407, India.
Why to publish with ISRP
- Open access options
- Ease of submission
- Rigorous review
- Rapid, high-quality publication
- High visibility and impact
Latest Articles | 2025 | Vol 05
by Priya G and Subana S
Department of Microbiology, Muthayammal College of Arts and Science,
Rasipuram, Namakkal, Tamilnadu, India
Abstract : The green synthesis of copper nanoparticles (CuNPs) using Bauhinia variegata leaf extract presents a cost-effective and environmentally sustainable approach to developing alternative antimicrobial agents. Bauhinia variegata is a medicinal plant rich in bioactive compounds, including anthraquinones, flavonoids, phenolic glycosides, alkaloids, saponins, reducing sugars, and tannins, which facilitate nanoparticle formation and stabilization. The synthesis of CuNPs was indicated by a color change from light to dark green and confirmed through UV-Vis spectroscopy and FTIR analysis, which identified key functional groups responsible for nanoparticle stabilization. The antibacterial potential of the synthesized CuNPs was evaluated against Pseudomonas spp., Klebsiella spp., and Staphylococcus spp., revealing significant inhibitory effects. Among the tested species, Pseudomonas spp. exhibited the highest susceptibility, while Staphylococcus spp. showed the lowest inhibition. Ethanol extracts demonstrated superior antimicrobial activity compared to other solvent extracts. These findings highlight the potential of Bauhinia variegata-mediated CuNPs as promising antimicrobial agents, particularly against multidrug-resistant bacterial strains. Further research should explore their mechanism of action and potential applications in pharmaceutical and biomedical fields..
by Perumal R and Subana S
Department of Microbiology, Muthayammal College of Arts and Science,
Rasipuram, Namakkal, Tamilnadu, India
Abstract : Cancer remains one of the leading causes of morbidity and mortality worldwide, driven by uncontrolled cell proliferation and resistance to apoptosis. Despite significant advances in cancer treatment, including surgery, chemotherapy, and radiation therapy, challenges such as drug resistance and adverse side effects continue to limit their effectiveness. Consequently, there has been a growing interest in exploring natural compounds with potential anticancer properties. Asparagus racemosus, a plant known for its medicinal properties, has garnered attention for its antioxidant and anticancer effects. This study investigates the bioactive extracts of Asparagus racemosus for their ability to induce cytotoxicity in liver cancer cells and modulate key genes involved in apoptosis, particularly the Bcl-2 gene. Our findings reveal that the plant extracts exhibit a dose-dependent reduction in cell viability and downregulate the Bcl-2 gene expression, suggesting that Asparagus racemosus has the potential to serve as an alternative or complementary cancer treatment. This research contributes to the expanding body of knowledge on plant-derived anticancer agents, highlighting Asparagus racemosus as a promising natural therapeutic candidate for liver cancer and other malignancies.